Microfluidic Hemostatic Scaffold Optimization

Design and prototype a microfluidic device capable of simulating interstitial flow to analyze the degradation rate of a synthetic hydrogel scaffold intended for rapid hemostasis. You must quantify the structural integrity of your material against shear stress levels ranging from 0.5 to 2.0 dyne/cm² while demonstrating precise control over localized fluid permeability. Document the trade-offs between scaffold cross-linking density, pore interconnectivity, and the resulting mass transport kinetics observed during your simulated vascular trauma trial.